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Overcharging Effect in Electrospray Ionization Mass Spectra of Daunomycin-Tuftsin Bioconjugates

Peptide-based small molecule drug conjugates for targeted tumor therapy are currently in the focus of intensive research. Anthracyclines, like daunomycin, are commonly used anticancer drug molecules and are also often applied in peptide-drug conjugates. However, lability of the O-glycosidic bond dur...

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Vydáno v:Molecules
Hlavní autoři: Pethő, Lilla, Mező, Gábor, Schlosser, Gitta
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720970/
https://ncbi.nlm.nih.gov/pubmed/31426442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24162981
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