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Development of novel cyclic NGR peptide–daunomycin conjugates with dual targeting property

Cyclic NGR peptides as homing devices are good candidates for the development of drug conjugates for targeted tumor therapy. In our previous study we reported that the Dau=Aoa-GFLGK(c[KNGRE]-GG-)-NH(2) conjugate has a significant antitumor activity against both CD13+ HT-1080 human fibrosarcoma and C...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Tripodi, Andrea Angelo Pierluigi, Tóth, Szilárd, Enyedi, Kata Nóra, Schlosser, Gitta, Szakács, Gergely, Mező, Gábor
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942373/
https://ncbi.nlm.nih.gov/pubmed/29765472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.78
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