A Ploidy Increase Promotes Sensitivity of Glioma Stem Cells to Aurora Kinases Inhibition

Glioma stem cells account for glioblastoma relapse and resistance to conventional therapies, and protein kinases, involved in the regulation of the mitotic machinery (i.e., Aurora kinases), have recently emerged as attractive therapeutic targets. In this study, we investigated the effect of Aurora k...

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Detalhes bibliográficos
Publicado no:J Oncol
Main Authors: Cilibrasi, Chiara, Guzzi, Andrèe, Bazzoni, Riccardo, Riva, Gabriele, Cadamuro, Massimiliano, Hochegger, Helfrid, Bentivegna, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720056/
https://ncbi.nlm.nih.gov/pubmed/31531022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9014045
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