A Ploidy Increase Promotes Sensitivity of Glioma Stem Cells to Aurora Kinases Inhibition

Glioma stem cells account for glioblastoma relapse and resistance to conventional therapies, and protein kinases, involved in the regulation of the mitotic machinery (i.e., Aurora kinases), have recently emerged as attractive therapeutic targets. In this study, we investigated the effect of Aurora k...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Oncol
Egile Nagusiak: Cilibrasi, Chiara, Guzzi, Andrèe, Bazzoni, Riccardo, Riva, Gabriele, Cadamuro, Massimiliano, Hochegger, Helfrid, Bentivegna, Angela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720056/
https://ncbi.nlm.nih.gov/pubmed/31531022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9014045
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