A Ploidy Increase Promotes Sensitivity of Glioma Stem Cells to Aurora Kinases Inhibition

Glioma stem cells account for glioblastoma relapse and resistance to conventional therapies, and protein kinases, involved in the regulation of the mitotic machinery (i.e., Aurora kinases), have recently emerged as attractive therapeutic targets. In this study, we investigated the effect of Aurora k...

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Bibliographische Detailangaben
Veröffentlicht in:J Oncol
Hauptverfasser: Cilibrasi, Chiara, Guzzi, Andrèe, Bazzoni, Riccardo, Riva, Gabriele, Cadamuro, Massimiliano, Hochegger, Helfrid, Bentivegna, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720056/
https://ncbi.nlm.nih.gov/pubmed/31531022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9014045
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