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Valproic Acid Inhibits Proliferation and Reduces Invasiveness in Glioma Stem Cells Through Wnt/β Catenin Signalling Activation

Glioblastoma is the most common malignant brain tumour in adults. The failure of current therapies can be ascribed to glioma stem cells (GSCs), which can rapidly repopulate the tumour following the initial treatment. The study of histone deacetylase inhibitors, such as valproic acid (VPA), is becomi...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Riva, Gabriele, Cilibrasi, Chiara, Bazzoni, Riccardo, Cadamuro, Massimiliano, Negroni, Caterina, Butta, Valentina, Strazzabosco, Mario, Dalprà, Leda, Lavitrano, Marialuisa, Bentivegna, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267016/
https://ncbi.nlm.nih.gov/pubmed/30373123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9110522
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