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Valproic Acid Inhibits Proliferation and Reduces Invasiveness in Glioma Stem Cells Through Wnt/β Catenin Signalling Activation

Glioblastoma is the most common malignant brain tumour in adults. The failure of current therapies can be ascribed to glioma stem cells (GSCs), which can rapidly repopulate the tumour following the initial treatment. The study of histone deacetylase inhibitors, such as valproic acid (VPA), is becomi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes (Basel)
Hauptverfasser: Riva, Gabriele, Cilibrasi, Chiara, Bazzoni, Riccardo, Cadamuro, Massimiliano, Negroni, Caterina, Butta, Valentina, Strazzabosco, Mario, Dalprà, Leda, Lavitrano, Marialuisa, Bentivegna, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267016/
https://ncbi.nlm.nih.gov/pubmed/30373123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9110522
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