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Efficacy of a Bispecific Antibody Co-Targeting VEGFA and Ang-2 in Combination with Chemotherapy in a Chemoresistant Colorectal Carcinoma Xenograft Model

Vascular endothelial growth factor (VEGF) inhibition by the addition of bevacizumab to the chemotherapy regimen of metastatic colorectal cancer leads to an improved outcome. However, anti-angiogenic tumor therapy targeting a single factor may be limited by complementary mechanisms. Angiopoietin-2 (A...

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Foilsithe in:Molecules
Main Authors: Mueller, Thomas, Freystein, Juana, Lucas, Henrike, Schmoll, Hans-Joachim
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719918/
https://ncbi.nlm.nih.gov/pubmed/31394786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24162865
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