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Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence

Colorectal carcinoma (CRC) constitutes a common malignancy with limited therapeutic options in metastasized stages. Mesenchymal stem cells (MSC) home to tumours and may therefore serve as a novel therapeutic tool for intratumoral delivery of antineoplastic factors. Tumour necrosis factor (TNF)-relat...

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Библиографические подробности
Главные авторы: Luetzkendorf, Jana, Mueller, Lutz P, Mueller, Thomas, Caysa, Henrike, Nerger, Katrin, Schmoll, Hans-Joachim
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822570/
https://ncbi.nlm.nih.gov/pubmed/19508388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00794.x
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