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Stability of Lentiviral Vector-Mediated Transgene Expression in the Brain in the Presence of Systemic Antivector Immune Responses

Lentiviral vectors are promising tools for gene therapy in the CNS. It is therefore important to characterize their interactions with the immune system in the CNS. This work characterizes transgene expression and brain inflammation in the presence or absence of immune responses generated after syste...

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Detalhes bibliográficos
Main Authors: ABORDO-ADESIDA, EVELYN, FOLLENZI, ANTONIA, BARCIA, CARLOS, SCIASCIA, SANDRA, CASTRO, MARIA G., NALDINI, LUIGI, LOWENSTEIN, PEDRO R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676203/
https://ncbi.nlm.nih.gov/pubmed/15960605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2005.16.741
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