Regulatable Gutless Adenovirus Vectors Sustain Inducible Transgene Expression in the Brain in the Presence of an Immune Response against Adenoviruses

In view of recent serious adverse events and advances in gene therapy technologies, the use of regulatable expression systems is becoming recognized as indispensable adjuncts to successful clinical gene therapy. In the present work we optimized high-capacity adenoviral (HC-Ad) vectors encoding the n...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xiong, Weidong, Goverdhana, Shyam, Sciascia, Sandra A., Candolfi, Marianela, Zirger, Jeffrey M., Barcia, Carlos, Curtin, James F., King, Gwendalyn D., Jaita, Gabriela, Liu, Chunyan, Kroeger, Kurt, Agadjanian, Hasmik, Medina-Kauwe, Lali, Palmer, Donna, Ng, Philip, Lowenstein, Pedro R., Castro, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317549/
https://ncbi.nlm.nih.gov/pubmed/16352528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.27-37.2006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados