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Preclinical Efficacy and Safety of an Anti-Human VEGFA and Anti-Human NRP1 Dual-Targeting Bispecific Antibody (IDB0076)

Although bevacizumab (Avastin(®)) has been approved as an antiangiogenic agent against some cancers, the efficacy is transient and unsatisfactory in other cancers most likely owing to the presence of alternative proangiogenic factors. Therefore, simultaneous blocking of several proangiogenic factors...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Ko, Jong-Hee, Kwon, Hyuk-Sang, Kim, Bomin, Min, Gihong, Shin, Chorong, Yang, Seok-Woo, Lee, Seong Wook, Lee, Youngmin, Hong, Dahae, Kim, Yong-Sung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356919/
https://ncbi.nlm.nih.gov/pubmed/32560565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060919
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