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MISTRG mice support engraftment and assessment of nonhuman primate hematopoietic stem and progenitor cells
Pre-clinical feasibility, safety, and efficacy testing of hematopoietic stem cell (HSC)-mediated gene therapy approaches is commonly performed in large animal models such as nonhuman primates (NHPs). Here we wished to determine whether mouse models would allow engraftment of NHP HSPCs which would en...
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| Veröffentlicht in: | Exp Hematol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719784/ https://ncbi.nlm.nih.gov/pubmed/30590092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2018.12.003 |
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