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Human hematopoietic stem cell maintenance and myeloid cell development in next-generation humanized mouse models

Next-generation humanized mice differentially support human HSPC maintenance and myelopoiesis. MISTRG mice support long-term human HSPC maintenance demonstrated by quaternary transplantation and development of human tissue macrophages.

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Sippel, Trisha R., Radtke, Stefan, Olsen, Tayla M., Kiem, Hans-Peter, Rongvaux, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373748/
https://ncbi.nlm.nih.gov/pubmed/30696625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018023887
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