Mechanistic and Fc requirements for inhibition of Sudan virus entry and in vivo protection by a synthetic antibody

The Sudan virus (SUDV), an ebolavirus, causes severe hemorrhagic fever with human case fatality rates of ~50%. Previous work from our lab demonstrated the synthetic antibody F4 potently inhibits viral entry and protects against lethal virus challenge in mice [Chen et al., ACS Chem. Biol., 2014, 9, 2...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunol Lett
Egile Nagusiak: Hofmann, Daniel, Zak, Samantha E., Nyakatura, Elisabeth K., Mittler, Eva, Bakken, Russell R., Chandran, Kartik, Dye, John M., Lai, Jonathan R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719535/
https://ncbi.nlm.nih.gov/pubmed/28890093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2017.09.002
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