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Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins
Filoviruses (family Filoviridae) include five ebolaviruses and Marburg virus. These pathogens cause a rapidly progressing and severe viral disease with high mortality rates (generally 30–90%). Outbreaks of filovirus disease are sporadic and, until recently, were limited to less than 500 cases. Howev...
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| 發表在: | J Biol Chem |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912469/ https://ncbi.nlm.nih.gov/pubmed/29500195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001627 |
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