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Mechanistic and Fc requirements for inhibition of Sudan virus entry and in vivo protection by a synthetic antibody
The Sudan virus (SUDV), an ebolavirus, causes severe hemorrhagic fever with human case fatality rates of ~50%. Previous work from our lab demonstrated the synthetic antibody F4 potently inhibits viral entry and protects against lethal virus challenge in mice [Chen et al., ACS Chem. Biol., 2014, 9, 2...
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| Udgivet i: | Immunol Lett |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719535/ https://ncbi.nlm.nih.gov/pubmed/28890093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2017.09.002 |
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