Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth

Regulated growth plate activity is essential for postnatal bone development and body stature, yet the systems regulating epiphyseal fusion are poorly understood. Here, we show that the tissue inhibitors of metalloprotease (TIMP) gene family is essential for normal bone growth after birth. Whole-body...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Saw, Sanjay, Aiken, Alison, Fang, Hui, McKee, Trevor D., Bregant, Sarah, Sanchez, Otto, Chen, Yan, Weiss, Ashley, Dickson, Brendan C., Czarny, Bertrand, Sinha, Ankit, Fosang, Amanda, Dive, Vincent, Waterhouse, Paul D., Kislinger, Thomas, Khokha, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719459/
https://ncbi.nlm.nih.gov/pubmed/31371388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201906059
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados