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Challenging the “chromatin hypothesis” of cardiac laminopathies with LMNA mutant iPS cells
Lamins A and C are intermediate filaments that provide structural support to the nuclear envelope and regulate gene expression. In this issue, Bertero et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902117) report that although lamin A/C haploinsufficient cardiomyocytes show disease-assoc...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719444/ https://ncbi.nlm.nih.gov/pubmed/31427369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907166 |
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