Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy

Mutations in A-type nuclear lamins cause dilated cardiomyopathy, which is postulated to result from dysregulated gene expression due to changes in chromatin organization into active and inactive compartments. To test this, we performed genome-wide chromosome conformation analyses in human induced pl...

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發表在:J Cell Biol
Main Authors: Bertero, Alessandro, Fields, Paul A., Smith, Alec S.T., Leonard, Andrea, Beussman, Kevin, Sniadecki, Nathan J., Kim, Deok-Ho, Tse, Hung-Fat, Pabon, Lil, Shendure, Jay, Noble, William S., Murry, Charles E.
格式: Artigo
語言:Inglês
出版: Rockefeller University Press 2019
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719452/
https://ncbi.nlm.nih.gov/pubmed/31395619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902117
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