Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy

Mutations in A-type nuclear lamins cause dilated cardiomyopathy, which is postulated to result from dysregulated gene expression due to changes in chromatin organization into active and inactive compartments. To test this, we performed genome-wide chromosome conformation analyses in human induced pl...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Bertero, Alessandro, Fields, Paul A., Smith, Alec S.T., Leonard, Andrea, Beussman, Kevin, Sniadecki, Nathan J., Kim, Deok-Ho, Tse, Hung-Fat, Pabon, Lil, Shendure, Jay, Noble, William S., Murry, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719452/
https://ncbi.nlm.nih.gov/pubmed/31395619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902117
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