Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer

High numbers of tissue-resident memory T (T(RM)) cells are associated with better clinical outcomes in cancer patients. However, the molecular characteristics that drive their efficient immune response to tumors are poorly understood. Here, single-cell and bulk transcriptomic analysis of T(RM) and n...

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Pubblicato in:J Exp Med
Autori principali: Clarke, James, Panwar, Bharat, Madrigal, Ariel, Singh, Divya, Gujar, Ravindra, Wood, Oliver, Chee, Serena J., Eschweiler, Simon, King, Emma V., Awad, Amiera S., Hanley, Christopher J., McCann, Katy J., Bhattacharyya, Sourya, Woo, Edwin, Alzetani, Aiman, Seumois, Grégory, Thomas, Gareth J., Ganesan, Anusha-Preethi, Friedmann, Peter S., Sanchez-Elsner, Tilman, Ay, Ferhat, Ottensmeier, Christian H., Vijayanand, Pandurangan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719422/
https://ncbi.nlm.nih.gov/pubmed/31227543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190249
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