Φορτώνει......
Enhanced nuclear protein export in premature aging and rescue of the progeria phenotype by modulation of CRM1 activity
The study of Hutchinson–Gilford progeria syndrome (HGPS) has provided important clues to decipher mechanisms underlying aging. Progerin, a mutant lamin A, disrupts nuclear envelope structure/function, with further impairment of multiple processes that culminate in senescence. Here, we demonstrate th...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Aging Cell |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718587/ https://ncbi.nlm.nih.gov/pubmed/31305018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13002 |
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