Repression of classical nuclear export by S-nitrosylation of CRM1

The karyopherin chromosomal region maintenance 1 (CRM1) is the major receptor for classical nuclear protein export. However, little is known about the regulation of CRM1 itself. Here, we report that cellular CRM1 became S-nitrosylated after extensive exposure to endogenous or exogenous nitric oxide...

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Hlavní autoři: Wang, Peng, Liu, Guang-Hui, Wu, Kaiyuan, Qu, Jing, Huang, Bo, Zhang, Xu, Zhou, XiXi, Gerace, Larry, Chen, Chang
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758806/
https://ncbi.nlm.nih.gov/pubmed/19812309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.057026
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