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Targeting breast cancer stem cells by a self-assembled, aptamer-conjugated DNA nanotrain with preloading doxorubicin

BACKGROUND: Cancer relapse and metastasis is an obstacle to the treatment of breast cancer. Breast cancer stem cells (BCSCs), which can evade the killing effect of traditional chemotherapies, such as doxorubicin (DOX), may contribute to cancer development. Therefore, it is necessary to develop novel...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Xu, Zhiyuan, Ni, Ronghua, Chen, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717853/
https://ncbi.nlm.nih.gov/pubmed/31695364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S200482
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