ATGL-1 mediates the effect of dietary restriction and the insulin/IGF-1 signaling pathway on longevity in C. elegans

OBJECTIVE: Animal lifespan is controlled through genetic pathways that are conserved from nematodes to humans. Lifespan-promoting conditions in nematodes include fasting and a reduction of insulin/IGF signaling. Here we aimed to investigate the input of the Caenorhabditis elegans homologue of the ma...

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Dades bibliogràfiques
Publicat a:Mol Metab
Autors principals: Zaarur, Nava, Desevin, Kathleen, Mackenzie, James, Lord, Avery, Grishok, Alla, Kandror, Konstantin V.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717769/
https://ncbi.nlm.nih.gov/pubmed/31311719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.07.001
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