A chromatin modifier integrates insulin/IGF‐1 signalling and dietary restriction to regulate longevity

Insulin/IGF‐1‐like signalling (IIS) and dietary restriction (DR) are the two major modulatory pathways controlling longevity across species. Here, we show that both pathways license a common chromatin modifier, ZFP‐1/AF10. The downstream transcription factors of the IIS and select DR pathways, DAF‐1...

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Vydáno v:Aging Cell
Hlavní autoři: Singh, Anupama, Kumar, Neeraj, Matai, Latika, Jain, Vaibhav, Garg, Amit, Mukhopadhyay, Arnab
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933660/
https://ncbi.nlm.nih.gov/pubmed/27039057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12477
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