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A chromatin modifier integrates insulin/IGF‐1 signalling and dietary restriction to regulate longevity
Insulin/IGF‐1‐like signalling (IIS) and dietary restriction (DR) are the two major modulatory pathways controlling longevity across species. Here, we show that both pathways license a common chromatin modifier, ZFP‐1/AF10. The downstream transcription factors of the IIS and select DR pathways, DAF‐1...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933660/ https://ncbi.nlm.nih.gov/pubmed/27039057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12477 |
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