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Methylation‐associated miR‐193b silencing activates master drivers of aggressive prostate cancer

Epigenetic silencing of miRNA is a primary mechanism of aberrant miRNA expression in cancer, and hypermethylation of miRNA promoters has been reported to contribute to prostate cancer initiation and progression. Recent data have shown that the miR‐193b promoter is hypermethylated in prostate cancer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Mazzu, Ying Z., Yoshikawa, Yuki, Nandakumar, Subhiksha, Chakraborty, Goutam, Armenia, Joshua, Jehane, Lina E., Lee, Gwo‐Shu Mary, Kantoff, Philip W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717747/
https://ncbi.nlm.nih.gov/pubmed/31225930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12536
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