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Methylation‐associated miR‐193b silencing activates master drivers of aggressive prostate cancer

Epigenetic silencing of miRNA is a primary mechanism of aberrant miRNA expression in cancer, and hypermethylation of miRNA promoters has been reported to contribute to prostate cancer initiation and progression. Recent data have shown that the miR‐193b promoter is hypermethylated in prostate cancer...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Mazzu, Ying Z., Yoshikawa, Yuki, Nandakumar, Subhiksha, Chakraborty, Goutam, Armenia, Joshua, Jehane, Lina E., Lee, Gwo‐Shu Mary, Kantoff, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717747/
https://ncbi.nlm.nih.gov/pubmed/31225930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12536
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