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Methylation‐associated miR‐193b silencing activates master drivers of aggressive prostate cancer

Epigenetic silencing of miRNA is a primary mechanism of aberrant miRNA expression in cancer, and hypermethylation of miRNA promoters has been reported to contribute to prostate cancer initiation and progression. Recent data have shown that the miR‐193b promoter is hypermethylated in prostate cancer...

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Detalles Bibliográficos
Publicado en:Mol Oncol
Main Authors: Mazzu, Ying Z., Yoshikawa, Yuki, Nandakumar, Subhiksha, Chakraborty, Goutam, Armenia, Joshua, Jehane, Lina E., Lee, Gwo‐Shu Mary, Kantoff, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717747/
https://ncbi.nlm.nih.gov/pubmed/31225930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12536
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