Exceptional responses with sequential metronomic temozolomide after pembrolizumab failure in patients with metastatic melanoma

Pembrolizumab is an effective therapy in patients with metastatic melanoma. However, not all patients derive benefit. It is postulated that an increase in regulatory T cells in melanoma patients can impair the response to immunotherapies. Continuous low dose temozolomide has shown to cause immunomod...

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Bibliografiske detaljer
Udgivet i:Melanoma Res
Main Authors: Swami, Umang, Monga, Varun, Freesmeier, Michele, Zhang, Weizhou, Bossler, Aaron D., Zakharia, Yousef, Milhem, Mohammed
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717692/
https://ncbi.nlm.nih.gov/pubmed/30829928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000592
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