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Efficacy and Adverse Events in Metastatic Melanoma Patients Treated with Combination BRAF Plus MEK Inhibitors Versus BRAF Inhibitors: A Systematic Review

We reviewed the literature to assess the efficacy and risk of constitutional, cardiac, gastrointestinal, and dermatological toxicities of combined BRAF plus MEK inhibitors versus BRAF inhibitors alone in patients with metastatic melanoma with BRAF mutations. Searches were conducted in PubMed, Cochra...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Greco, Austin, Safi, Danish, Swami, Umang, Ginader, Tim, Milhem, Mohammed, Zakharia, Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966686/
https://ncbi.nlm.nih.gov/pubmed/31817473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121950
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