Efficacy and Adverse Events in Metastatic Melanoma Patients Treated with Combination BRAF Plus MEK Inhibitors Versus BRAF Inhibitors: A Systematic Review

We reviewed the literature to assess the efficacy and risk of constitutional, cardiac, gastrointestinal, and dermatological toxicities of combined BRAF plus MEK inhibitors versus BRAF inhibitors alone in patients with metastatic melanoma with BRAF mutations. Searches were conducted in PubMed, Cochra...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Greco, Austin, Safi, Danish, Swami, Umang, Ginader, Tim, Milhem, Mohammed, Zakharia, Yousef
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966686/
https://ncbi.nlm.nih.gov/pubmed/31817473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121950
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