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Single-cell transcriptional profiling reveals the heterogenicity in colorectal cancer

BACKGROUND: Colorectal Cancer (CRC) is a highly heterogeneous disease. RNA profiles of bulk tumors have enabled transcriptional classification of CRC. However, such ways of sequencing can only target a cell colony and obscure the signatures of distinct cell populations. Alternatively, single-cell RN...

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Détails bibliographiques
Publié dans:Medicine (Baltimore)
Auteurs principaux: Dai, Weier, Zhou, Fangbin, Tang, Donge, Lin, Liewen, Zou, Chang, Tan, Wenyong, Dai, Yong
Format: Artigo
Langue:Inglês
Publié: Wolters Kluwer Health 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716720/
https://ncbi.nlm.nih.gov/pubmed/31441872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000016916
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