Evaluation of the contribution of germline variants in BRCA1 and BRCA2 to uveal and cutaneous melanoma

Germline mutations of BRCA1 and BRCA2 predispose individuals to a high risk of breast and ovarian cancer, and elevated risk of other cancers, including those of the pancreas and prostate. BRCA2 mutation carriers may have increased risk of uveal melanoma (UM) and cutaneous melanoma (CM), but associat...

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Publicado en:Melanoma Res
Autores principales: Johansson, Peter A., Nathan, Vaishnavi, Bourke, Lauren M., Palmer, Jane M., Zhang, Tongwu, Symmons, Judith, Howlie, Madeleine, Patch, Ann-Marie, Read, Jazlyn, Holland, Elizabeth A., Schmid, Helen, Warrier, Sunil, Glasson, William, Höiom, Veronica, Wadt, Karin, Jönsson, Göran, Olsson, Håkan, Ingvar, Christian, Mann, Graham, Brown, Kevin M., Hayward, Nicholas K., Pritchard, Antonia L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716616/
https://ncbi.nlm.nih.gov/pubmed/31464824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000613
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