Long Non-coding RNA HOTTIP Promotes CCL3 Expression and Induces Cartilage Degradation by Sponging miR-455-3p

Long non-coding RNAs (lncRNAs) play pivotal roles in diseases such as osteoarthritis (OA). However, knowledge of the biological roles of lncRNAs is limited in OA. We aimed to explore the biological function and molecular mechanism of HOTTIP in chondrogenesis and cartilage degradation. We used the hu...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Mao, Guping, Kang, Yan, Lin, Ruifu, Hu, Shu, Zhang, Ziji, Li, Hongyi, Liao, Weiming, Zhang, Zhiqi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716540/
https://ncbi.nlm.nih.gov/pubmed/31508417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00161
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