RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration

RAD6 participates in DNA double-strand breaks (DSBs) repair by ubiquitinating histone H2B in mitotic cells. In terminally differentiated cells, however, the mechanisms of DNA damage repair are less well known. In this study, we investigate whether RAD6B is involved in DSBs repair in neurons and effe...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Guo, Zhao, Tian, Yingxia, Guo, Yingli, Li, Boya, Liu, Xiangwen, Xie, Kun, Song, Yanfeng, Wang, Degui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716356/
https://ncbi.nlm.nih.gov/pubmed/31507381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00392
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