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RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration

RAD6 participates in DNA double-strand breaks (DSBs) repair by ubiquitinating histone H2B in mitotic cells. In terminally differentiated cells, however, the mechanisms of DNA damage repair are less well known. In this study, we investigate whether RAD6B is involved in DSBs repair in neurons and effe...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Guo, Zhao, Tian, Yingxia, Guo, Yingli, Li, Boya, Liu, Xiangwen, Xie, Kun, Song, Yanfeng, Wang, Degui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716356/
https://ncbi.nlm.nih.gov/pubmed/31507381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00392
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