Downregulation of FGF Signaling by Spry4 Overexpression Leads to Shape Impairment, Enamel Irregularities, and Delayed Signaling Center Formation in the Mouse Molar

FGF signaling plays a critical role in tooth development, and mutations in modulators of this pathway produce a number of striking phenotypes. However, many aspects of the role of the FGF pathway in regulating the morphological features and the mineral quality of the dentition remain unknown. Here,...

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Vydáno v:JBMR Plus
Hlavní autoři: Marangoni, Pauline, Charles, Cyril, Ahn, Youngwook, Seidel, Kerstin, Jheon, Andrew, Ganss, Bernhard, Krumlauf, Robb, Viriot, Laurent, Klein, Ophir D
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Special Issue
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715786/
https://ncbi.nlm.nih.gov/pubmed/31485553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10205
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