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Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

Mice carrying mutations in Wise (Sostdc1) display defects in many aspects of tooth development, including tooth number, size and cusp pattern. To understand the basis of these defects, we have investigated the pathways modulated by Wise in tooth development. We present evidence that, in tooth develo...

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Detalles Bibliográficos
Publicado en:Development
Main Authors: Ahn, Youngwook, Sanderson, Brian W., Klein, Ophir D., Krumlauf, Robb
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512258/
https://ncbi.nlm.nih.gov/pubmed/20724449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.054668
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