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Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

Mice carrying mutations in Wise (Sostdc1) display defects in many aspects of tooth development, including tooth number, size and cusp pattern. To understand the basis of these defects, we have investigated the pathways modulated by Wise in tooth development. We present evidence that, in tooth develo...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Ahn, Youngwook, Sanderson, Brian W., Klein, Ophir D., Krumlauf, Robb
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512258/
https://ncbi.nlm.nih.gov/pubmed/20724449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.054668
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