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Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

Mice carrying mutations in Wise (Sostdc1) display defects in many aspects of tooth development, including tooth number, size and cusp pattern. To understand the basis of these defects, we have investigated the pathways modulated by Wise in tooth development. We present evidence that, in tooth develo...

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Publicat a:Development
Autors principals: Ahn, Youngwook, Sanderson, Brian W., Klein, Ophir D., Krumlauf, Robb
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512258/
https://ncbi.nlm.nih.gov/pubmed/20724449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.054668
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