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Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

Mice carrying mutations in Wise (Sostdc1) display defects in many aspects of tooth development, including tooth number, size and cusp pattern. To understand the basis of these defects, we have investigated the pathways modulated by Wise in tooth development. We present evidence that, in tooth develo...

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Publicado en:Development
Autores principales: Ahn, Youngwook, Sanderson, Brian W., Klein, Ophir D., Krumlauf, Robb
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512258/
https://ncbi.nlm.nih.gov/pubmed/20724449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.054668
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