Distinct methylation levels of mature microRNAs in gastrointestinal cancers

The biological significance of micro (mi)RNAs has traditionally been evaluated according to their RNA expression levels based on the assumption that miRNAs recognize and regulate their targets in an unvarying fashion. Here we show that a fraction of mature miRNAs including miR-17-5p, -21-5p, and -20...

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Vydáno v:Nat Commun
Hlavní autoři: Konno, Masamitsu, Koseki, Jun, Asai, Ayumu, Yamagata, Akira, Shimamura, Teppei, Motooka, Daisuke, Okuzaki, Daisuke, Kawamoto, Koichi, Mizushima, Tsunekazu, Eguchi, Hidetoshi, Takiguchi, Shuji, Satoh, Taroh, Mimori, Koshi, Ochiya, Takahiro, Doki, Yuichiro, Ofusa, Ken, Mori, Masaki, Ishii, Hideshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715669/
https://ncbi.nlm.nih.gov/pubmed/31467274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11826-1
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