Cardiac MLC2 kinase is localized to the Z-disc and interacts with α-actinin2

Cardiac contractility is enhanced by phosphorylation of myosin light chain 2 (MLC2) by cardiac-specific MLC kinase (cMLCK), located at the neck region of myosin heavy chain. In normal mouse and human hearts, the level of phosphorylation is maintained relatively constant, at around 30–40% of total ML...

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Publicado no:Sci Rep
Main Authors: X. Cai, Lawrence, Tanada, Yohei, D. Bello, Gregory, C. Fleming, James, F. Alkassis, Fariz, Ladd, Thomas, Golde, Todd, Koh, Jin, Chen, Sixue, Kasahara, Hideko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715661/
https://ncbi.nlm.nih.gov/pubmed/31467300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48884-w
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