טוען...

α-Actinin2 is required for the lateral alignment of Z discs and ventricular chamber enlargement during zebrafish cardiogenesis

α-Actinin2 (Actn2) is a predominant protein in the sarcomere Z disc whose mutation can lead to cardiomyopathy. However, the function of Actn2 in Z-disc assembly and cardiomyopathy in vertebrates remains elusive. We leveraged genetic tools in zebrafish embryos to elucidate the function of Actn2. We i...

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מידע ביבליוגרפי
Main Authors: Yang, Jingchun, Xu, Xiaolei
פורמט: Artigo
שפה:Inglês
יצא לאור: Federation of American Societies for Experimental Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448773/
https://ncbi.nlm.nih.gov/pubmed/22767232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-207969
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