Načítá se...

α-Actinin2 is required for the lateral alignment of Z discs and ventricular chamber enlargement during zebrafish cardiogenesis

α-Actinin2 (Actn2) is a predominant protein in the sarcomere Z disc whose mutation can lead to cardiomyopathy. However, the function of Actn2 in Z-disc assembly and cardiomyopathy in vertebrates remains elusive. We leveraged genetic tools in zebrafish embryos to elucidate the function of Actn2. We i...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yang, Jingchun, Xu, Xiaolei
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448773/
https://ncbi.nlm.nih.gov/pubmed/22767232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-207969
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!