Bystander responses impact accurate detection of murine and human antigen-specific CD8(+) T cells

Induction of memory CD8(+) T cells is important for controlling infections such as malaria and HIV/AIDS and for cancer immunotherapy. Accurate assessment of antigen-specific (Ag-specific) CD8(+) T cells is critical for vaccine optimization and for defining correlates of protection. However, conditio...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Martin, Matthew D., Jensen, Isaac J., Ishizuka, Andrew S., Lefebvre, Mitchell, Shan, Qiang, Xue, Hai-Hui, Harty, John T., Seder, Robert A., Badovinac, Vladimir P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715387/
https://ncbi.nlm.nih.gov/pubmed/31219804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124443
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