β Cell–intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion

β-Arrestin 1 and 2 (Barr1 and Barr2, respectively) are intracellular signaling molecules that regulate many important metabolic functions. We previously demonstrated that mice lacking Barr2 selectively in pancreatic β cells showed pronounced metabolic impairments. Here we investigated whether Barr1...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Barella, Luiz F., Rossi, Mario, Zhu, Lu, Cui, Yinghong, Mei, Fang C., Cheng, Xiaodong, Chen, Wei, Gurevich, Vsevolod V., Wess, Jürgen
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
Subjects:
Concise Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715363/
https://ncbi.nlm.nih.gov/pubmed/31184597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126309
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