Direct detection of early-stage cancers using circulating tumor DNA

Early detection and intervention are likely to be the most effective means for reducing morbidity and mortality of human cancer. However, development of methods for non-invasive detection of early stage tumors has remained a challenge. We have developed an approach called targeted error correction s...

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Veröffentlicht in:Sci Transl Med
Hauptverfasser: Phallen, Jillian, Sausen, Mark, Adleff, Vilmos, Leal, Alessandro, Hruban, Carolyn, White, James, Anagnostou, Valsamo, Fiksel, Jacob, Cristiano, Stephen, Papp, Eniko, Speir, Savannah, Reinert, Thomas, Orntoft, Mai-Britt Worm, Woodward, Brian D., Murphy, Derek, Parpart-Li, Sonya, Riley, David, Nesselbush, Monica, Sengamalay, Naomi, Georgiadis, Andrew, Li, Qing Kay, Madsen, Mogens Rørbæk, Mortensen, Frank Viborg, Huiskens, Joost, Punt, Cornelis, van Grieken, Nicole, Fijneman, Remond, Meijer, Gerrit, Husain, Hatim, Scharpf, Robert B., Diaz, Luis A., Jones, Siân, Angiuoli, Sam, Ørntoft, Torben, Nielsen, Hans Jørgen, Andersen, Claus Lindbjerg, Velculescu, Victor E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714979/
https://ncbi.nlm.nih.gov/pubmed/28814544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan2415
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