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Design and Use of Chikungunya Virus Replication Templates Utilizing Mammalian and Mosquito RNA Polymerase I-Mediated Transcription

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus. It has a positive-sense RNA genome that also serves as the mRNA for four nonstructural proteins (nsPs) representing subunits of the viral replicase. Coupling of nsP and RNA synthesis complicates analysis of viral RNA replication. We developed...

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Foilsithe in:J Virol
Main Authors: Utt, Age, Rausalu, Kai, Jakobson, Madis, Männik, Andres, Alphey, Luke, Fragkoudis, Rennos, Merits, Andres
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714806/
https://ncbi.nlm.nih.gov/pubmed/31217251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00794-19
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