NPM1 as a potential therapeutic target for atypical teratoid/rhabdoid tumors

BACKGROUND: Atypical teratoid/rhabdoid tumors (AT/RTs) are highly malignant brain tumors with inactivation of the SMARCB1 gene, which play a critical role in genomic transcriptional control. In this study, we analyzed the genomic and transcriptomic profiles of human AT/RTs to discover new druggable...

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Vydáno v:BMC Cancer
Hlavní autoři: Phi, Ji Hoon, Sun, Choong-Hyun, Lee, Se-Hoon, Lee, Seungmook, Park, Inho, Choi, Seung Ah, Park, Sung-Hye, Lee, Ji Yeoun, Wang, Kyu-Chang, Kim, Seung-Ki, Yun, Hongseok, Park, Chul-Kee
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714307/
https://ncbi.nlm.nih.gov/pubmed/31462227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6044-z
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