Repositioning disulfiram as a radiosensitizer against atypical teratoid/rhabdoid tumor

BACKGROUND. Atypical teratoid/rhabdoid tumor (AT/RT) is one of the most common malignant brain tumors in infants. Although cancer stem cells of AT/RT express aldehyde dehydrogenase (ALDH), effective chemotherapies against AT/RT have not been established. Here, we examined radiosensitizing effects of...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Lee, Young Eun, Choi, Seung Ah, Kwack, Pil Ae, Kim, Hak Jae, Kim, Il Han, Wang, Kyu-Chang, Phi, Ji Hoon, Lee, Ji Yeoun, Chong, Sangjoon, Park, Sung-Hye, Park, Kyung Duk, Hwang, Do Won, Joo, Kyeung Min, Kim, Seung-Ki
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570172/
https://ncbi.nlm.nih.gov/pubmed/28340172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now300
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