Disulfiram modulates stemness and metabolism of brain tumor initiating cells in atypical teratoid/rhabdoid tumors

BACKGROUND: Atypical teratoid/rhabdoid tumors (AT/RT) are among the most malignant pediatric brain tumors. Cells from brain tumors with high aldehyde dehydrogenase (ALDH) activity have a number of characteristics that are similar to brain tumor initiating cells (BTICs). This study aimed to evaluate...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Choi, Seung Ah, Choi, Jung Won, Wang, Kyu-Chang, Phi, Ji Hoon, Lee, Ji Yeoun, Park, Kyung Duk, Eum, Dayoung, Park, Sung-Hye, Kim, Il Han, Kim, Seung-Ki
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483115/
https://ncbi.nlm.nih.gov/pubmed/25378634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou305
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