Brain Death Enhances Activation of the Innate Immune System and Leads to Reduced Renal Metabolic Gene Expression

BACKGROUND: Brain-death associated inflammation has been implicated in decreased kidney allograft function and survival, but the underlying mechanisms have not been well distinguished from the conditions of critical care itself. We have developed a clinically translatable model to separate and inves...

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Bibliografiske detaljer
Udgivet i:Transplantation
Main Authors: Zitur, Laura J., Chlebeck, Peter J., Odorico, Scott K., Danobeitia, Juan S., Zens, Tiffany J., Van Kooten, Cees, Eerhart, Michael, Reyes, Jose A., Springer, Megan L., Coonen, Jennifer M., Brunner, Kevin G, Capuano, Saverio V., D’Alessandro, Anthony M., Fernandez, Luis A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713605/
https://ncbi.nlm.nih.gov/pubmed/30964836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002744
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